Clarksville is located in Pike County Missouri on the bank of the Mississippi River and at the heart of Missouri’s Great River Road, Highway 79. The town overlooks the mighty Mississippi at the location of the U.S. Lock and Dam 24, and rests at the foot of Lookout Point / Sky Lift Hill, one of the highest points on the Mississippi River. Climb to the top, and enjoy an 800 square mile view of the river and valley. We’re so close to the River, the shop owners and barge pilots keep each other honest. The River flows by us in the hot summers, and jams with ice in the the cold winters. But potters, glass blowers, jewelry designers, antique dealers, furniture makers, and specialty craftsmen keep us anchored here year round.

Each winter Bald Eagles migrate in numbers to fish the turbulent downstream waters of Lock and Dam 24. If ice jams the northern Mississippi River, Clarksville’s Bald Eagle count increases since they can always fish the open water the Dam creates. We celebrate this migration every January during our ‘Eagle Days’ weekend. Plan a visit for amazing views of wild and world bird sancuary Eagles.

Perfectly placed between St. Charles and Hannibal Missouri, Clarksville offers a truely unique stop on an historic route of travel. Experience Clarksville, and experience life on the Mississippi.

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  1. I am hoping to bike through Clarksville as part of a 300-mile solo ride in a few weeks. Can someone please email me (thbutterfield@gmail.com) to answer some questions I have about your town? Thank you!

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